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　　According to China News Service, on November 7, 2018, Henan Jufeel International Group receives the patent certificate of "The Method of Preparing Lyophilized Powder for Injection Comparising Aloe and Panax Pseudo-ginseng" from the United States Patent and Trademark Office, certificate number:US10016366, document number :CN1504005US, patentee: Zhang Rongxuan.

　　On May 31, 2018, the company receives the U.S. patent and trademark office examiners official approval letter, the application number: US15/011450, the international PCT patent number: PCT/CN2013/00129710/282013.

　　This anti - aging, young - state biotechnology officially received the patent certificate of invention today. It demonstrates that the patent Jufeel company has been approved by the United States patent and trademark office and international market and protected internationally, after 1013 days (From the date of submission on January 29, 2016 till now) of intense scrutiny.

　　Aloe acemannan, a bioactive substance composition extracted from aloe vera through the patent technology, has the function of promoting human body secretion of Estrogen estradiol directly without any side effect. Thus, it is known as "natural aloe plant estrogen", also known as "PMAS".

　　According to media reports, on August 30, 2018, the special research on the influence of PMAS on the clinical symptoms of menopausal women is launched at the general hospital (301 hospital) of the people's liberation army (PLA).

　　As early as December 2014, Zhang Rongxuan leads a research team to co-write the medical paper PMAS Estrogen-like Effect Research, which is published in the national medical journal "Journal of Chinese Medicine" 2014 issue B12. In February 2015, the team once again writes the medical paper Research on the Activation of Immune Function by PMAS, which is published in the national medical journal Guide of Chinese Medicine , volume 13, issue 4, February 2015. These two papers arouse a lot of discussions on the female hormone secretion by PMAS in the industry and attract the attention of the whole industry.

　　The team have studied PMAS for years and find that PMAS has a surprisingly Inverse growth effect. This kind of active material discovered in aloe vera can make cell division frequency increase, can force decaying or ageing cell to be activated afresh or be eliminated, make the organ that functions decrepit returns vigor thereby.

　　PMAS can rapidly reach the subcutaneous tissue of human body through capillaries stimulating the division of skin cells, and greatly improve the skin issues of roughness, darkness, pigmentation, acne, etc., function of human body has overall improvement. Thus the speed of cell renewal is accelerated, the endocrine is balanced, the autoimmunity is improved, and the metabolism is vigorous.

　　PMAS not only improves people's physical appearance, but also, more importantly, makes people physically younger, so as to restore the function of organs with declining functions. This is undoubtedly a good opportunity for people to realize their dreams brought by the development of science and the progress of scientific research.