Pursuant to the information of Jufeel Group, the company received the United States patent and trademark office’s official Approval letter of the patent of Method of Preparing Lyophilized Powder for Injection Comprsing Aloe and Panax Pseudoginseng on May 31st, 2018; patent application number: US15/011450, International PCT invention patent number: PCT/CN2013/001297 10/282013. It demonstrates that the top biological extraction technology patent of "Anti-aging·Youthful Appearance" of Jufeel company has been approved by the United States patent and trademark office and international market and protected internationally, after two years (From the date of submission on January 29, 2016 till now) of intense scrutiny.

　　Aloe acemannan, a bioactive substance composition extracted from aloe vera through the patent technology, has the function of promoting human body secretion of Estrogen estradiol directly without any side effect. Thus, it is known as "natural aloe plant estrogen", also known as "PMAS".

　　PMAS is a reverse growth factor firstly proposed and proved by the research team of Jufeel Natural Drug R&D Center of School of Pharmacy and Life Sciences of Changzhou University, led by Jufeel Biology chief scientist professor Zhang Rongxuan. It is also a kind of aloe vera biological preparation that can rapidly recover the deficiency of immune system.

　　In 1996, the Food and Agriculture Organization of the United Nations praised aloe vera as "the best health food for human in the 21st century" in the global wild plant evaluation. Aloe vera food research has been extensively developed since the 1960s. As the most essential substance in aloe polysaccharide, PMAS can stimulate and promote estrogen level, improve the internal tissue function of organs, enhance the elasticity of skin collagen and fibrin, activate hormones, regulate endocrine system, especially gonads and adrenals, improve sexual function and delay menopause. It has the advantage of being a genuine anti-aging product taking effect from the inside of human body. PMAS is extracted from aloe polysaccharide without any additives of cellular active substances, so there are no side effects on the human body.

　　After 15 years of research, Professor Zhang Rongxuan found that: the number of human cell division is proportional to the life span, and human aging is due to the cell (most basic component of body life) decaying. After 30 years old, with the increase of age, the regeneration and division of cells are gradually slow; and the accumulation of aging cells makes the organ function constantly decline, and even makes the organ pathological changes; people also become old and sick. The injection of high-purity PMAS which has the anti-aging and anti-growth effect, can accelerate the growth of new cells in the human body, peel off the aging and diseased cells, and return the human body to a young state.

　　Through a series of comparisons, Jufeel PMAS is easier to use than stem cells without procedures of virus screening. Jufeel PMAS is cheaper and more suitable for public use than sheep placenta; Jufeel PMAS is safer to use than botulinum toxin and does not cause toxic side effects.

　　It is well known that Jufeel company is not only the inventor and manufacturer of the international plant living cell anti-aging technology and bio-immunized glycan purification technology - PMAS, but also a well-known aloe organic planter and aloe drug research organization in China. Over the years, with the advanced concept of “Let life science and technology serve humanity better”, Jufeel company has provided perfect and efficient aloe health and overall solutions to human beings from different angles and levels in ecology, nutrition, health care, beauty and pharmaceuticals. Professor Zhang Rongxuan, the chairman of Jufeel company, is an internationally renowned AIDS prevention expert and a member of the Henan Jiu San Society. He has shouldered the social mission for 18 years and devoted himself to research and development of aloe products, and strives to create a globally influential aloe enterprise, shows the top technology strength to the world.