Recent days a high-tech enterprise called Kaifeng JUFEEL Biology Technology Co., Ltd. has cooperated with Zhejiang University and signed the cooperation agreement as Using new type of natural polysaccharide PMAS as active target of new Anti-HIV and effective dosage-form development, the cooperation between school and enterprise provides new medicament and new treatment strategy for solving the global public health issues.

　　As we know, the two sides previously have research and discovered an acemannan material that extracted from aloe, Pure Material Acemannan Source, PMAS, which has stimulate effectiveness to human immune system, up-regulation the number of CD4 cell of HIV patient, therefore it has the effectiveness for enhance the entirety immune system, for the further step of develop to PMAS as the clinical application, which was aimed at discovery of non-protease inhibitors and non chemical drug, and also conveniently and safely using new anti-HIV virus without any venenous side-effect. The R & D target will research and develop the active target and effective dosage-form of new medical drug, as the pre-clinical pharmacological basis of new type of medicament.

　　For the both side of JUFEEL and Zhejiang University will not only achieve the influence of immunocyte proliferation and adjustment of PMAS in different dosages and interaction times, to pick up the best ones and develop the new anti-HIV medicament by March, 2020; but also will achieve the effectiveness and functionevaluation of PMAS works on macrophages and CD8+T, therefore to set up a new product path and provide practical foundation for clinical research, by March, 2021; besides, collect the experimental data, analyse the experimental result, deal with conclusion through the R & D, new product R & D, promote and spread the science achievement, participate in the clinical research and declare the patent and global tech invention award in both of domestic and abroad, all by March, 2023.

　　PMAS is an auxiliary therapeutic drug which is the main biological agent extracts from Acemannan from natural Aloe Vera. Meanwhile to quickly enhance on human immune ability, so that achieve to curbing the viral replication from AIDS. So far this invention patent of “injection method that uses the freeze-dry powder to boosts stimulation of estrogen secretion by aloe preparation” has already passed the trademark office approval letter by the U.S. Patent and International PCT invention patent code is: PCT/CN2013/001297 10/282013.